Plant Sciences Institute Faculty Scholars
(Scholars sorted by last name in ascending order)
Second Cohort26H-Index2,600+Citations(Google Scholar)
Sotirios Archontoulis is an Associate Professor in the Department of Agronomy. His research interests include cropping systems analysis, crop simulation modeling and digital agriculture. His research program focuses on deeper understanding Genotype x Environment x Management interactions, adding mechanistic algorithms into crop models to better simulate soil-plant-atmosphere processes and expression of genotypes in the field, and on developing web-tools to disseminate research results in real-time to stakeholders. Archontoulis' research group uses field experimentation and computer simulation modeling to predict impacts (e.g., yield forecasting, the FACTS project), explain causes and design strategies to improve production and environmental performance of U.S. Midwestern cropping systems under current and future climate.
Second Cohort30H-Index2,600+Citations(Google Scholar)William T. Frankenberger Professor of Soil Science
Michael Castellano is a Professor in the Department of Agronomy and William T. Frankenberger Professor of Soil Science. His research advances our basic understanding of nutrient dynamics across the plant-soil-atmosphere continuum to improve the productivity and environmental performance of cropping systems.
Dr. Castellano's PSI project addresses the roles of environment and management on phenotype. Soil properties and management interact to have large effects on resource availability within and across fields. His research group uses experiments, innovative sensing technologies and process-based modeling to observe, predict and explain 1) how variation in resource availability affects phenotype; and 2) what phenotypes perform best in particular combinations of environment and management.
First Cohort26H-Index3,100+Citations(Google Scholar)Northrop Grumman Professor
Liang Dong is a Professor in the Department of Computer and Electrical Engineering. His research interests include Micro/Nano-Electro-Mechanical Systems (MEMS/NEMS), lab on a chip, microfluidics, optics and smart materials and structures and their applications in sustainable agriculture; biomedicine, renewable energy; and information technology. As an engineer in the area of Micro-Electro-Mechanical Systems, Dr. Dong develops small-scale devices with critical dimensions ranging from micrometers to millimeters through inexpensive fabrication processes. He also integrates these devices into sensor networks for large-scale, high-throughput, in-field measurements.
Dr. Dong's PSI project focuses on developing and deploying inexpensive microscale sensors and biochips for direct measurement of important chemical and physical signals related to plant responses to various environmental stresses.
First Cohort33H-Index4,400+Citations(Google Scholar)Joseph C. and Elizabeth A. Anderlik Professor in Engineering
Baskar Ganapathysubramanian is a Professor in the Department of Mechanical Engineering. His research interests are in the areas of computational mechanics, physics and scientific computing. His lab leverages advances in applied mathematics and high-performance computing to model, design and control real-world physical phenomena. From the application point-of-view, his lab is particularly interested in energy and environment-related phenomena. They develop mathematical techniques and computational tools -- model reduction, multi-scale frameworks, multi-physics simulators, control algorithms, data-driven methods to efficiently model these systems. Whenever possible, they validate the techniques using the expertise of their experimental collaborators.
Dr. Ganapathysubramanian's PSI project focuses on high-throughput algorithms for image processing, data dimensionality reduction, as well as mechanistic models of plant growth.
First Cohort67H-Index15,100+Citations(Google Scholar)Charles F. Curtiss Distinguished Professor
Stephen Howell is a Distinguished Professor in the Department of Genetics, Development and Cell Biology. His research focuses on abiotic stresses, such as heat, drought, flooding and salt stress, the major causes of crop losses worldwide. Stress tolerance has become an even more important trait as we face the prospects of climate change. His lab studies how plants perceive and respond to environmental stresses through a mechanism called the Unfolded Protein Response (UPR).
Dr. Howell's PSI project is a two-pronged approach: The first is to identify genetic determinants in plant populations that confer stress tolerance and the second is to modulate the expression of genes encoding known components on the UPR signaling pathway. This involves defining the UPR signaling network composed of genes that are upregulated or downregulated by stress and characterizing the stress tolerance in UPR mutants during vegetative and reproductive development. This information will help scientists predict gene edits that might best contribute to stress tolerance phenotypes.
Second Cohort22H-Index1,900+Citations(Google Scholar)
Guiping Hu is an Associate Professor in the Department of Industrial Manufacturing Systems Engineering. Her research interests include supply chain design, operational planning, decision making and data analytics with applications in manufacturing production, renewable energy, plant breeding and sustainable agriculture.
Dr. Hu's PSI project aims to develop a system engineering approach to analyze and advance the plant breeding process through optimized management and planning. This will be achieved by designing a multi-scale decision making framework that combines mathematical programming, decision making, simulation theory and management principles. The mathematical decision making model will provide quantitative decision support for customized plant breeding process with the focus on field testing, deployment and agronomic management. Careful considerations will be given to the modeling framework so that probabilistic nature of plant growth and dynamic time dependent phenomenon can be incorporated.
Dr. Hu's team plans to construct a rational and interdisciplinary platform to analyze, advance and optimize plant breeding process through optimized management and planning. The PSI project will focus on analyzing and managing the resources in the plant breeding process and subsequent agriculture production. Decision making models will be designed with a focus on breeding process planning, resource allocation and agronomic management. The research project will fill the gap between the lack of research in the planning and management strategies in plant breeding and field production and challenges in breeding that would benefit from more sophisticated and efficient planning and management decision making at different stag tag-noteses and various scales in the plant breeding process.
First Cohort30H-Index3,700+Citations(Google Scholar)
Carolyn Lawrence-Dill is a Professor in the Departments of Agronomy and Genetics, Development and Cell Biology. Her research program is devoted to developing computational systems that support the plant research community. Her lab's work enables the use of existing and emerging knowledge to establish common standards and methods for data collection, integration, and sharing.
Dr. Lawrence-Dill's predictive plant phenomics project focuses on three areas: Developing standards that democratize data access and analysis and enable community development of systems that interoperate; creating examples of successful phenotypic prediction enabled by developed standards, a proof of concept, and to advance novel concepts for downstream broad implementation; and developing a coordinated network of research groups to develop and deploy data standards relevant to genotypic diversity, environmental documentation, and phenotypic prediction.
Second Cohort26H-Index3,700+Citations(Google Scholar)
Peng Liu is a Professor in the Department of Statistics. Her research interests include statistical genomics, bioinformatics and high-dimensionalomicsdata analysis. Motivated by the statistical challenges of analyzing big biological data from modern high-throughput technologies, Dr. Liu has been working on developing novel statistical methods for exploring, mining and drawing inference with the available high-dimensional data.
With the advance of technologies, it is much easier now to collect huge amounts of data, such as phenomic, metabolomic, transcriptomic and microbiomic data, from a single study. However, the computational methods are far behind from efficiently utilizing all available data sources to dissect complex biological processes and predict phenotypes. Dr. Liu's PSI project focuses on developing novel and robust statistical methods to jointly model large, differentomicsdatasets and build an integrative statistical analysis.
First Cohort51H-Index8,300+Citations(Google Scholar)Kenneth J. Frey Chair in Agronomy
Thomas Lübberstedt is the Director of R.F. Baker Center for Plant Breeding, Professor in the Department of Agronomy, and the K.J. Frey Chair in Agronomy. His general research area is the application/development of tools and methods provided by genome analysis to understand the composition of complex traits and phenomena, using this knowledge to determine and exploit genetic diversity in elite and exotic germplasm, and then applying this knowledge to plant breeding. Crop focus is on maize and perennial grasses. Current activities focus on accelerating plant breeding by establishing and improving doubled haploid technologies in maize and other species.
Dr. Lübberstedt's PSI research project addresses the fundamental question of why and how plants with only a single genome (haploids) differ from perfect isogenic genotypes with two identical genomes (isogenic doubled haploids). This information will ultimately be used to establish high-throughput procedures to select for haploid plantlets or cells in vitro. His research group is utilizinggermplasm enhancement in maize(GEM) DH lines, which were established in collaboration with the USDA to incorporate exotic germplasm into elite germplasm. These GEM-DH lines are currently used in genome-wide association studies of agronomic as well as root and phytohormone-related traits in collaboration with engineers to identify valuable exotic alleles.
Second Cohort30H-Index3,800+Citations(Google Scholar)
Fernando Miguez is an Associate Professor in the Department of Agronomy. His research group uses a combination of field experimentation and mathematical and statistical models to understand a cropping system's productivity, soil health and ecosystem services related to carbon, water and nitrogen dynamics. Dr. Miguez's group has investigated a wide range of crops and management practices such as bioenergy crops, cover crops, biochar application and crop rotations.
A formidable challenge in plant biology has been the dissection of genetic by environment interactions. Dr. Miguez's PSI project proposes to develop physiologically robust mathematical models and combine them with computationally intensive statistical methods to improve crop performance prediction. If they can develop models that are complex enough to capture the underlying physiological mechanisms, but simple enough so that they can understand them, they will be able to capture the non-linear behaviors that are responsible for many of the observed genetic by environment interactions.
First Cohort52H-Index8,100+Citations(Google Scholar)
Allen Miller is a Professor in the Departments of Plant Pathology and Microbiology and Biochemistry, Biophysics and Molecular Biology. His research program employs plant viruses as easy-to-use model systems to provide the basic understanding of how viruses express genes and replicate. Because of similarities across kingdoms, this knowledge may be relevant to major human viruses. The lab focuses on viral RNA structures that recruit host translation factors in novel ways, providing a better understanding of how the genetic code can be decoded. In addition to revealing targets for engineered virus resistance in crop plants, this knowledge may allow modification of viral sequences to regulate viral and host gene expression in beneficial ways.
Dr. Miller's PSI project focuses on developing a new technology called ribosome profiling to monitor global gene expression at the level of protein synthesis. The lab is performing RNAseq on every segment of mRNA being translated by a ribosome. This provides a more reliable measure of gene expression than traditional RNAseq, which simply sequences all the mRNAs. Ribosome profiling indicates how much each of those mRNAs is actually being translated into protein, the ultimate step in gene expression that leads from genotype to phenotype. It also reveals new genes, not known previously because they lack conventional signals in their sequences, a common occurrence in viruses. The lab will apply this tool to understand how virus infection, which is heavily controlled at the level of translation, affects translation of the host transcriptome. This will provide valuable insight into how the virus hijacks cellular gene expression to its own advantag tag-notese, which may ultimately suggest virus resistance strategies that disrupt virus-host interactions.
First Cohort60H-Index15,400+Citations(Google Scholar)Distinguished ProfessorLaurence H. Baker Endowed Chair
Dan Nettleton is a Distinguished Professor and Chair of the Department of Statistics, Laurence H. Baker Endowed Chair, and Director of the Laurence H. Baker Center for Bioinformatics and Biological Statistics, His research interests include statistical design and analysis of high-throughput experiments in biology and the development of statistical learning methods for prediction.
Dr. Nettleton's PSI project has established a statistical research group consisting of faculty and graduate students in the department of statistics who are developing statistical methods for predicting phenotypes from genotypic and environmental data. Specific projects include the prediction of yield for a given variety in a given environment using historical yield trial results and weather information as training data, the prediction of multiple plant traits from DNA marker data and spatial locations of plants in a field, the prediction of plant phenotypes from DNA marker data combined with transcriptomic data and improvement of the random forest methodology for general prediction problems.
First Cohort19H-Index1,500+Citations(Google Scholar)
Maria Salas Fernandez is an Associate Professor in the Department of Agronomy. Her research program is devoted to developing superior sorghum lines to be used as lignocellulosic feedstock for biofuel production and to discovering genes/alleles associated with traits that confer superior biomass yield through the use of molecular and genomic technologies. The genetic knowledge generated in her research program will be applied to sorghum but could also be utilized for the genetic improvement of other crops. Sorghum was selected as the crop focus based on the genotypic and phenotypic variation of the species, and its potential as a biofuel source. Sorghum can be used to produce ethanol from grain, stover, sugars accumulated in the stems (sweet sorghums) or as a dedicated lignocellulosic biomass crop (particularly photoperiod-sensitive types).
Dr. Salas Fernandez's PSI project includes designing and developing high-yielding sorghum ideotypes through operations research; determining the relationship between photosynthesis and biomass accumulation under drought assessed by high-throughput image analysis; and utilizing natural variation in photosynthetic capacity to model sorghum biomass production and adaption using a mechanistic framework.
Second Cohort31H-Index3,500+Citations(Google Scholar)
Soumik Sarkar is an Associate Professor in the Department of Mechanical Engineering. His research focuses on development of data analytics and machine learning algorithms for autonomous perception and decision-making in complex cyber-physical systems with a large variety of application areas including building energy systems, plant science and agriculture, design and manufacturing, and intelligent transportation systems. The nature of his research is inherently multi-disciplinary, involving machine learning, information theory, theory of computation, dynamical systems, topology and statistical mechanics.
Today, precise and cost-effective sensors as well as high performance computing technologies are looking to transform traditional agriculture into an efficient cyber-physical system. In this context, engineers and computer scientists have a major role to play, and Dr. Sarkar's vision is to become one such enabler who can contribute to this critical societal need.
Dr. Sarkar's PSI project includes high-risk, high-gain ideas at the juncture of machine learning, artificial intelligence and plant science/agriculture. Specifically, he will develop advanced spatiotemporal data analytics and information fusion techniques to solve phenomics problems in plant pathology and plant breeding, and enable smart farming practices. Examples of Dr. Sarkar's projects will include developing deep learning based techniques for high-throughput plant stress phenotyping using heterogeneous data. He is also involved in the ISU Yield Prediction Task Force project that focuses on development machine learning frameworks for county-level corn yield prediction using long-term historical data involving weather and other environmental information, economic data, as well as management practices.
First Cohort76H-Index23,200+Citations(Google Scholar)Charles F. Curtiss Distinguished ProfessorIowa Corn Promotion Board Endowed Chair in GeneticsBaker Scholar of Agricultural Entrepreneurship
Patrick Schnable is a Charles F. Curtiss Distinguished Professor in the Department of Agronomy, Iowa Corn Promotion Board Endowed Chair in Genetics, and Baker Scholar of Agricultural Entrepreneurship. He manages a research program that emphasizes interdisciplinary approaches to understanding plant biology. His own expertise is in the areas of genetics, molecular biology, genomics, bioinformatics, and high-throughput phenotyping but he collaborates with researchers in diverse fields, including agricultural and computer engineering, plant breeding, statistics and soil science. He is the director of the Plant Sciences Institute, and under his direction, the Plant Sciences Institute's Faculty Scholars are pursuing unique interdisciplinary approaches to the field of predictive plant phenomics.
Dr. Schnable's scientific investigations of the maize genome have been wide-ranging and he has developed and/or deployed a number of important genomic tools and resources. However, the focus of his PSI project is on constructing and deploying new sensors and robots to facilitate the automated collection of the large volumes of phenotypic data at multiple locations needed to develop an understanding of GxE interactions. For example, networked systems of hundreds of computer-controlled cameras that enable high-throughput, high-resolution, field-based time-lapse photography for studying maize growth/development and responses to environmental stresses have been deployed at multiple locations over multiple years.
Second Cohort31H-Index2,900+Citations(Google Scholar)
Asheesh K. Singh (Danny) is a Professor and Monsanto Chair in Soybean Breeding in the Department of Agronomy. His team focusses on soybean cultivar development for conventional markets. The team is most interested in the development of prescriptive cultivars that are tailored for stakeholders' requirements. Conceptually, a prescriptive cultivar is a variety that is developed for a specific agronomic production system and environment using genetic knowledge, rational breeding designs and selection strategies to combine the prescribed characteristics. Predictive phenomics is a fundamental requirement for developing prescriptive cultivars as a deeper understanding of the genotype, environment and phenotype and their interactions are needed for variety development and its placement.
Dr. Singh's PSI project will utilize high-throughput phenomics (using ground and aerial imaging systems and different sensors) linked with genomic technologies to generate, analyze and interpret data using computational tools such as machine learning and methods for predictions in non-linear systems. With the use of sensors and data analytics methods, they are seeking to develop interpretive models to elucidate genetic-physiological mechanisms for yield improvements (of associated above ground and root traits) in diverse production practices, and generate new biological insights, develop new methods for analyzing phenomics-related data sets and create new tools that will deepen our trait understanding. They are also interested in robotics-assisted breeding through the development and deployment of ground and aerial robotics in a networked connection for saliency driven phenotyping with the intent to remove and/or minimize measurement variability and improve breeding designs.
First Cohort25H-Index2,100+Citations(Google Scholar)
Lie Tang is a Professor in the Department of Agricultural and Biosystems Engineering. He is an expert in developing various automation and robotic systems for agricultural and biological applications.
Dr. Tang's PSI project encompasses a broad range of robotic systems including high-throughput robotic phenotyping; robotic weed control; autonomous field robot navigation control and operational path optimization; and machine vision algorithms for plant and animal monitoring and characterization.
Second Cohort19H-Index1,900+Citations(Google Scholar)
Justin Walley is a Professor in the Department of Plant Pathology and Microbiology. His research program is focused on understanding how plants perceive and respond to environmental stresses. His lab specializes in mass spectrometry based proteomics to globally quantify protein abundance and post-translational modifications. They also use systems biology approaches to integrate these data with other types of omics datasets, such as transcriptome profiling, to generate predictive models of biological processes.
Dr. Walley's PSI project is focused on identifying genetic factors that regulate resistance of corn to Northern Corn Leaf Blight (NLB). Towards this goal multi-scale high-throughput measurements of field grown corn infected with NLB will be collected and integrated in order to construct a predicative model of disease resistance.
First Cohort22H-Index1,600+Citations(Google Scholar)
Lizhi Wang is an Associate Professor in the Department of Industrial Manufacturing Systems Engineering. His research interests include bilevel optimization algorithm design, plant breeding, power systems modeling and analysis, manufacturing supply chain, and transportation system resiliency assessment and enhancement.
Dr. Wang's PSI project includes two focus areas. The first is designing new genomic selection strategies using operations research. The objective is to optimize a set of phenotypes, e.g., high yield with herbicide resistance, within a certain number of breeding generations subject to a budget constraint. The second is the detection of epistatic effects. Integer programming models are being developed to detect epistatic effects from genotype and phenotype data sets.
First Cohort44H-Index9,400+Citations(Google Scholar)
Steven Whitham is a Professor in the Department of Plant Pathology and Microbiology. His research focuses on the molecular mechanisms that underlie plant interactions with viruses and fungi. Projects in his lab involve studies on the major row crop plants, soybean and corn, as well as utilizing model host plants such as Arabidopsis thaliana and Nicotiana benthamiana. The lab uses functional genomics approaches to study the molecular changes that occur in susceptible and resistant genotypes of crop and model plant species. The plant and pathogen genes identified in these studies are providing insight into the ways successful pathogens interact with and manipulate their hosts and by which plants deploy defense mechanisms.
Dr. Whitham's PSI project stems from his lab's work to develop virus-based tools for functional genomics in plants. Using a technology known as virus-induced gene silencing, the researchers can program viruses to turn off any plant gene to study the functions of that gene in plant processes. They are interested in using virus-induced gene silencing in large-scale screens designed to identify plants genes that mediate defense against pathogens and the trade-offs between plant defenses versus growth. The large-scale screens they envision will be enabled by automated systems for collecting and analyzing image and spectral data that will enhance their ability to associate plant genes with phenotypes of interest.
First Cohort43H-Index15,000+Citations(Google Scholar)
Yanhai Yin is the Department Chair and Professor in the Department of Genetics, Development and Cell Biology. His research is focused on understanding the molecular mechanisms and gene regulatory networks through which the plant steroid hormone, Brassinosteroid (BRs), regulates plant growth and stress responses. His lab uses a combination of genetics, genomics, computational modeling and predictive phenomic approaches and the model plant Arabidopsis thaliana in the research. The long-term goal is to apply the knowledge generated from model systems to improve crop production under adverse climate conditions.
Dr. Yin's PSI project is a collaboration with several research groups in developing new phenotyping tools that can be used to study the functions of a large number of genes in Gene Regulatory Networks (GRNs). These include developing a platform to phenotype plant growth under drought conditions and using the platform to study the functions of hundreds of genes identified by computational modeling and quantitative genetics. The goal is to establish relationship between GRNs generated from predictive modeling and plant performance under various stress conditions.
First Cohort48H-Index16,000+Citations(Google Scholar)Pioneer Distinguished Chair in Maize Breeding
Jianming Yu is a Professor and Pioneer Distinguished Chair in Maize Breeding in the in the Department of Agronomy and Pioneer Distinguished Chair in Maize Breeding. The focus of his research is to address significant questions in plant breeding by combining cutting-edge genomic technologies and quantitative genetics theories. His research integrates knowledge in plant breeding, quantitative genetics, genomics, molecular genetics and statistics, and has the ultimate goal of developing and implementing new strategies and methods in trait dissection and crop improvement.
Dr. Yu's PSI project focuses on establishing an integrated modeling approach for performance prediction. Three major areas of research can be identified as the key elements to establish an Integrated Modeling Approach for Performance Prediction (IMAPP): quantitative and population genetics framework and associated developments; crop physiological modeling and agriculture production system; and systems biology. All three areas have their advantag tag-noteses and disadvantag tag-noteses in modeling and performance prediction at different levels, e.g., number of genotypes, context of performance, and input and output. In this project, the objectives are to assess a diverse set of performance prediction modeling approaches in plant breeding and genetics, crop modeling, and gene regulatory network, and to develop an integrated modeling framework for performance prediction under varied conditions.